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Mesothelioma The Deadly Effect of Asbestos

Friday, April 23, 2010 ·

To provide hope and life-saving treatment to the thousands of people dying each year from asbestos cancer or asbestos-caused mesothelioma, federal governments of affected countries must make substantial investments into medical research.

Asbestos must be banned in the United States and in other developed countries to protect future generations from increased proliferation of this deadly disease.

Mesothelioma: A Terrible Killer

Mesothelioma is an extremely painful, almost always fatal cancer in which membrane cells (mesothelium) lining the chest or abdomen become malignant and multiply and divide without control. The resulting tumor thickens and hardens, crushing the lungs and suffocating the patient, invading the chest wall causing severe difficulty in breathing and sometimes invading other vital organs like the heart, aorta or the abdomen, leading to various forms of the cancer.

We are all at risk

Mesothelioma is the tragic legacy of the industrial and commercial use of asbestos.Advertised as “the miracle mineral” because of its excellent fireproofing, insulating, filling and bonding properties, asbestos was used virtually everywhere in industry,manufacturing and construction from the 1930s through the late 1970s, even as its carcinogenic and respiratory lethality was well known to medicine, industry and the government. At its peak usage, more than 3,000 industrial applications or products were listed as utilizing asbestos.

As a result, over 20 million American workers were exposed to this mineral and are at risk of developing mesothelioma today, according to the Environmental Protection Agency (EPA). When the workers in the asbestos related industries brought the fibers home on their skin, hair and clothes, their families were also exposed to the dangerous mineral.

Asbestos was prevalent on Navy ships, and servicemen and shipyard workers were heavily exposed. A study at the Groton, Connecticut shipyard found that over one hundred thousand workers had been exposed to asbestos over the years at just this one shipyard.

Mesothelioma has a long incubation period before its symptoms start to show (ten to 50 years), and even low-dose, incidental exposures to asbestos are sufficient to cause the cancer. Thus, the prolific exposures of the past are leading to an epidemic of disease today. Minnesota Congressman Bruce Vento worked near an asbestos-insulated boiler in a Minneapolis brewery for two summers while putting himself through college. In October 2000, he was diagnosed with mesothelioma, and died just ten months later.

According to the most recent data released by the Centers for Disease Control and Prevention, in 2004, approximately2,700 Americans died from mesothelioma, and incidence still has not peaked.

Millions more Americans are being put at risk today, because of all of the asbestos that remains present in occupational settings; in buildings such as homes, offices and schools; and in a wide variety of products. Just one product, an insulation contaminated with a very dangerous form of asbestos, is estimated by the EPA to be in 30 million U.S.homes.

The EPA estimates that there are asbestos containing materials in most of the nation's approximately 107,000 primary and secondary schools and 733,000 public and commercial buildings. According to the US Department of Labor’s Occupational Safety and Health Administration (OSHA), an “estimated 1.3 million employees in construction and general industry face significant asbestos exposure on the job.” The utility tunnels under our nation’s Capitol have hazardous levels of asbestos, and demonstrate just how pervasive the problem is.

In fact, asbestos still has not been banned. Every year, the hazards of asbestos increases as more of the carcinogen is introduced into our environment. Asbestos is still used in roofing and other building materials, and in many consumer products including vehicle brakes. As a result, everyday occurrences like going to work, simple remodeling projects, or the normal wear of roofing materials, tiles or brakes on a family vehicle are exposing Americans to the hazardous risk of mesothelioma.

Needed: A National Commitment to a Cure

Mesothelioma was identified in medical literature by the late 1940’s. However, for decades the need for research to develop effective treatments for mesothelioma patients was ignored, obscured by the legal, economic and political aspects of asbestos.

The National Cancer Institute’s annual investment in clinical mesothelioma research has been, on a per death basis, only a fraction of its investment in other cancers. For years,despite the disproportionate toll of the disease on Navy veterans and shipyard workers,the Department of Defense did not apply any of its vast biomedical research resources to mesothelioma.

As a result of the Meso Foundation’s advocacy efforts, in 2008mesothelioma investigators are for the first time eligible to compete for Department of Defense Peer Reviewed Medical Research Grant funding. No mesothelioma grants have yet been awarded, however, this has led to advancements in the treatment of mesothelioma lagging far behind those of other cancers. According to the National Institutes of Health, the median survival of mesothelioma patients is only 14 months, with most patients dying within two years.

But there is hope. Since 1999, the Mesothelioma Applied Research Foundation has awarded over $5 million to spur mesothelioma research forward. Researchers are gaining valuable understandings of the tumor and potential treatment targets, and new clinical trials are opening. The field is ripe for federal partnership. Federal investment in the research needed to develop earlier detection and more effective treatment is essential to provide hope to the thousands of Americans who will become sick as a result of asbestos exposures that have already occurred or that will inevitably occur given the virtual ubiquity of asbestos in our environment.

The proliferation of asbestos cancer or asbestos-disease must be stopped. Over 40 developed and industrialized countries have already banned asbestos; the United States should also protect its citizens by enacting an immediate asbestos ban.

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